Recent Publications

METC Affilates in Bold


  • Galen W. Heyne, Joshua L. Everson, Lydia J. Ansen-Wilson, Cal G. Melberg, Dustin M. Fink, Kia F. Parins, Padydeh Doroodchi, Caden M. Ulschmid, Robert J. Lipinski. Gli2 gene dosage and gene-environment interaction illuminate the etiological complexity of holoprosencephaly. Disease Models & Mechanisms 2016 : doi: 10.1242/dmm.026328
  • Chesney A, Booth CJ, Lietz CB, Li L, Pedersen JA. Peroxymonosulfate Rapidly Inactivates the Disease-associated Prion Protein. Environ Sci Technol. 2016 Jun 1. [Epub ahead of print]. PMID: 27247993.
  • Fei P, Palenski TL, Wang S, Gurel Z, Hankenson KD, Sorenson CM, Sheibani N. Thrombospondin-2 Expression During Retinal Vascular Development and Neovascularization. J Ocul Pharmacol Ther. 2015 Sep;31(7):429-44. doi: 10.1089/jop.2014.0151. Epub 2015 May 7. PMID: 25950258.
  • Burns FR, Lanham KA, Xiong KM, Gooding AJ, Peterson RE, Heideman W. Analysis of the Zebrafish sox9b Promoter: Identifiecation of Elements that Recapitulate Organ-Specific Expression of sox9b. Gene. 2016 Mar 10; 578(2): 281-9. doi: 10.1016/j.gene.2015.12.041. Epub 2015 Dec 2013. PMID: 26721460.
  • Guo W, Yu D, Wang X, Luo C, Chen Y, Lei W, Wang C, Ge Y, Xue W, Tian Q, Gao X, Yao W. Anti-inflammatory effects of Interleukin-23 receptor cytokine-binding homology region rebalance T cell distribution in rodent collagen-induced arthritis. Oncotarget. 2016 May 11. doi: 10.18632/oncotarget.9309. [Epub ahead of print] PMID: 27177334
  • Moore RW, Fritz WA, Schneider AJ, Lin TM, Branam AM, Safe S, Peterson RE. 2,3,7,8-Tetrachlorodibenzo-p-dioxin has both pro-carcinogenic and anti-carcinogenic effects on neuroendocrine prostate carcinoma formation in TRAMP mice. Toxicol Appl Pharmacol. 2016 May 2. pii: S0041-008X(16)30099-0. doi: 10.1016/j.taap.2016.04.018. PMID: 27151233
  • Brody MJ, Feng L, Grimes AC, Hacker TA, Olson TM, Kamp TJ, Balijepalli RC, Lee Y. LRRC10 is required to maintain cardiac function in response to pressure overload. Am J Physiol Heart Circ Physiol. 2016 Jan 15;310(2):H269-78. doi: 10.1152/ajpheart.00717.2014. Epub 2015 Nov 25. PMID: 26608339
  • Blanke KL, Sacco JC, Millikan RC, Olshan AF, Luo J, Trepanier LA. Polymorphisms in the carcinogen detoxification genes CYB5A and CYB5R3 and breast cancer risk in African American women. Cancer Causes Control. 2014 Nov;25(11):1513-21. doi: 10.1007/s10552-014-0454-7. Epub 2014 Sep 16. PMID: 25225034. PMCID: PMC4216608.
  • Bushkofsky JR, Maguire M, Larsen MC, Fong YH, Jefcoate CR. Cyp1b1 affects external control of mouse hepatocytes, fatty acid homeostasis and signaling involving HNF4α and PPARα. Arch Biochem Biophys. 2016 May 1;597:30-47. doi: 10.1016/ Epub 2016 Mar 29. PMID: 27036855. PMCID: PMC4868071.
  • Zhang F, Adnani N, Vazquez-Rivera E, Braun DR, Tonelli M, Andes DR, Bugni TS. Application of 3D NMR for Structure Determination of Peptide Natural Products. J Org Chem. 2015 Sep 4;80(17):8713-9. doi: 10.1021/acs.joc.5b01486. Epub 2015 Aug 21. PMID: 26273993. PMCID: PMC4696765
  • Park HS, Yu YM, Lee MK, Maeng PJ, Kim SC, Yu JH. Velvet-mediated repression of β-glucan synthesis in Aspergillus nidulans spores. Sci Rep. 2015 May 11;5:10199. doi: 10.1038/srep10199. PMID: 25960370. PMCID: 4426670.
  • Verant ML, Bohuski EA, Lorch JM, Blehert DS. Optimized methods for total nucleic acid extraction and quantification of the bat white-nose syndrome fungus, Pseudogymnoascus destructans, from swab and environmental samples. J Vet Diagn Invest. 2016 Mar;28(2):110-8. doi: 10.1177/1040638715626963. PMID: 26965231
  • Ricke WA, Lee CW, Clapper TR, Schneider AJ, Moore RW, Keil KP, Abler LL, Wynder JL, López Alvarado A, Beaubrun I, Vo J, Bauman TM, Ricke EA, Peterson RE, Vezina CM. In utero and Lactational TCDD Exposure Increases Susceptibility to Lower Urinary Tract Dysfunction in Adulthood. Toxicol Sci. 2016 Apr;150(2):429-40. doi: PMID: 26865671
  • Park HS, Yu JH. Developmental regulators in Aspergillus fumigatus. J Microbiol. 2016 Mar;54(3):223-31. doi: 10.1007/s12275-016-5619-5. Epub 2016 Feb 27. PMID: 26920882.
  • Leiter É, Park HS, Kwon NJ, Han KH, Emri T, Oláh V, Mészáros I, Dienes B, Vincze J, Csernoch L, Yu JH, Pócsi I. Characterization of the aodA, dnmA, mnSOD and pimA genes in Aspergillus nidulans. Sci Rep. 2016 Feb 5;6:20523. doi: 10.1038/srep20523. PMID: 26846452. PMCID: PMC4742808
  • Lee S, Shatadal S, Griep AE. Dlg-1 Interacts With and Regulates the Activities of Fibroblast Growth Factor Receptors and EphA2 in the Mouse Lens. Invest Ophthalmol Vis Sci. 2016 Feb 1;57(2):707-18. doi: 10.1167/iovs.15-17727. PMID: 26906157. PMCID: PMC4771194
  • Barkal LJ, Theberge AB, Guo CJ, Spraker J, Rappert L, Berthier J, Brakke KA, Wang CC, Beebe DJ, Keller NP, Berthier E. Microbial metabolomics in open microscale platforms. Nat Commun. 2016 Feb 4;7:10610. doi: 10.1038/ncomms10610. PMID: 26842393. PMCID: PMC4742997.
  • Clements J, Schoville S, Peterson N, Lan Q, Groves RL. Characterizing Molecular Mechanisms of Imidacloprid Resistance in Select Populations of Leptinotarsa decemlineata in the Central Sands Region of Wisconsin. PLoS One. 2016 Jan 28;11(1):e0147844. doi: 10.1371/journal.pone.0147844. eCollection 2016. PMID: 26821361. PMCID: PMC4731083.


  • Ricke WA, Lee CW, Clapper TR, Schneider AJ, Moore RW, Keil KP, Abler LL, Wynder JL, López Alvarado A*, Beaubrun I*, Vo J*, Bauman TM, Ricke EA, Peterson RE, and Vezina CM. 2015. In utero and Lactational TCDD Exposure Increases Susceptibility to Lower Urinary Tract Dysfunction in Adulthood. Toxicol Sci In press.
    *2014 METC undergraduate summer scholars
  • Goodson WH 3rd, et al (Curran C). Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead. Carcinogenesis. 2015 Jun; 36 Supl 1: S254-96. doi: 10.1093/carcin/bgv039. PMID: 26106142. PMCID: PMC4480130.
  • Casey SC, et al (Curran). The effect of environmental chemicals on the tumor microenvironment. Carcinogenesis. 2015 Jun; 36 Suppl 1: S160-83. doi: 10.1093/carcin/bgv035. PMID: 26106136. PMCID: PMC44565612.
  • Irving AA, Plum LA, Blaser WJ, Ford MR, Weng C, Clipson L, DeLuca HF, Dove WF. Cholecalciferol or 25-hydroxycholecalciferol neither prevents nor treats adenomas in a rat model of familial colon cancer. J Nutr. 2015 Feb;145(2):291-8.
  • Goswami S, Tarapore RS, Poenitzsch Strong AM, TeSlaa JJ, Grinblat Y, Setaluri V, Spiegelman VS. MicroRNA-340-mediated degradation of microphthalmia-associated transcription factor (MITF) mRNA is inhibited by coding region determinant-binding protein (CRD-BP). J Biol Chem. 2015 Jan 2;290(1):384-95.
  • Wong L, Hutson PR, Bushman W. Resolution of chronic bacterial-induced prostatic inflammation reverses established fibrosis. Prostate. 2015 Jan;75(1):23-32.
  • O’Leary KA, Shea MP, Schuler LA. Modeling Prolactin Actions in Breast Cancer In Vivo: Insights from the NRL-PRL Mouse. Adv Exp Med Biol. 2015;846:201-20.
  • Curran CS, Carrillo ER, Ponik SM, Keely PJ. Collagen density regulates xenobiotic and hypoxic response of mammary epithelial cells. Environ Toxicol Pharmacol. 2015 Jan;39(1):114-24.


  • Johnson BP, Walisser JA, Liu Y, Shen AL, McDearmon EL, Moran SM, McIntosh BE, Vollrath AL, Schook AC, Takahashi JS, Bradfield CA. Hepatocyte circadian clock controls acetaminophen bioactivation through NADPH-cytochrome P450 oxidoreductase. Proc Natl Acad Sci U S A. 2014 Dec 30;111(52):18757-62.
  • Rodríguez CI, Setaluri V. Cyclic AMP (cAMP) signaling in melanocytes andmelanoma. Arch Biochem Biophys. 2014 Dec 1;563:22-7.  Review.
  • Poenitzsch Strong AM, Setaluri V, Spiegelman VS. MicroRNA-340 as a modulator of RAS-RAF-MAPK signaling in melanoma. Arch Biochem Biophys. 2014 Dec 1;563:118-24.
  • Baker TR, King-Heiden TC, Peterson RE, Heideman W. Dioxin induction of transgenerational inheritance of disease in zebrafish. Mol Cell Endocrinol. 2014 Dec;398(1-2):36-41.
  • Cholewa BD, Pellitteri-Hahn MC, Scarlett CO, Ahmad N. Large-scale label-free comparative proteomics analysis of polo-like kinase 1 inhibition via the small-molecule inhibitor BI 6727 (Volasertib) in BRAF(V600E) mutant melanoma cells. J Proteome Res. 2014 Nov 7;13(11):5041-50.
  • Ivancic MM, Irving AA, Jonakin KG, Dove WF, Sussman MR. The concentrations of EGFR, LRG1, ITIH4, and F5 in serum correlate with the number of colonic adenomas in ApcPirc/+ rats. Cancer Prev Res (Phila). 2014 Nov;7(11):1160-9.
  • Irving AA, Yoshimi K, Hart ML, Parker T, Clipson L, Ford MR, Kuramoto T, Dove WF, Amos-Landgraf JM. The utility of Apc-mutant rats in modeling human colon cancer. Dis Model Mech. 2014 Nov;7(11):1215-25.
  • Blanke KL, Sacco JC, Millikan RC, Olshan AF, Luo J, Trepanier LA. Polymorphisms in the carcinogen detoxification genes CYB5A and CYB5R3 and breast cancer risk in African American women. Cancer Causes Control. 2014 Nov;25(11):1513-21.
  • Singh A, Singh A, Sand JM, Bauer SJ, Bin Hafeez B, Meske L, Verma AK. Topically Applied Hsp90 Inhibitor 17AAG Inhibits UVR-Induced Cutaneous Squamous Cell Carcinomas. J Invest Dermatol. 2014 Oct 22.
    Schneider AJ, Branam AM, Peterson RE. Intersection of AHR and Wnt signaling in development, health, and disease. Int J Mol Sci. 2014 Oct 3;15(10):17852-85.
  • Carney CM, Muszynski JL, Strotman LN, Lewis SR, O’Connell RL, Beebe DJ, Theberge AB, Jorgensen JS. Cellular microenvironment dictates androgen production by murine fetal Leydig cells in primary culture. Biol Reprod. 2014 Oct;91(4):85.
  • Liu Y, Johnson BP, Shen AL, Wallisser JA, Krentz KJ, Moran SM, Sullivan R, Glover E, Parlow AF, Drinkwater NR, Schuler LA, Bradfield CA. Loss of BMAL1 in ovarian steroidogenic cells results in implantation failure in female mice. Proc Natl Acad Sci U S A. 2014 Sep 30;111(39):14295-300.
  • Schneider AJ, Moore RW, Branam AM, Abler LL, Keil KP, Mehta V, Vezina CM, Peterson RE. In utero exposure to TCDD alters Wnt signaling during mouse prostate development: linking ventral prostate agenesis to downregulated -catenin signaling. Toxicol Sci. 2014 Sep;141(1):176-87
  • Lanham KA, Plavicki J, Peterson RE, Heideman W. Cardiac myocyte-specific AHR activation phenocopies TCDD-induced toxicity in zebrafish. Toxicol Sci. 2014 Sep;141(1):141-54.
  • Sengupta S, Johnson BP, Swanson SA, Stewart R, Bradfield CA, Thomson JA. Aggregate culture of human embryonic stem cell-derived hepatocytes in suspension are an improved in vitro model for drug metabolism and toxicity testing. Toxicol Sci. 2014 Jul;140(1):236-45.
  • Brinkman AM, Wu J, Ersland K, Xu W. Estrogen receptor and aryl hydrocarbon receptor independent growth inhibitory effects of aminoflavone in breast cancer cells. BMC Cancer. 2014 May 20;14:344.
  • Rodríguez CI, Setaluri V. Resistance to MAPK inhibition: come see(c) AMPed up melanoma. Pigment Cell Melanoma Res. 2014 May;27(3):323-5.
  • Shetty A, Hickey WJ. Effects of outer membrane vesicle formation, surface-layer production and nanopod development on the metabolism of phenanthrene by Delftia acidovorans Cs1-4. PLoS One. 2014 Mar 18;9(3):e92143.