Welcome to the Molecular & Environmental Toxicology Center


The Molecular and Environmental Toxicology Center (METC) at the University of Wisconsin–Madison focuses on biochemistry, carcinogenesis, cell biology, developmental biology, genetics, genomics, immunology, neurobiology, proteomics, and xenobiotic fate and metabolism research in a collaborative, interdisciplinary community of high-caliber students, faculty members, and facilities.

The Center houses an interdisciplinary graduate program, a summer research program, and two NIEHS training grants. Our T32 grant, T32ES007015, supports 8 predoctoral trainees and 3 postdoctoral trainees each year. Our R25 grant, R25ES020720 , supports 6 undergraduate researchers from underrepresented ethinic/racial groups each summer.

The METC is administratively housed in the UW School of Medicine and Public Health (SMPH), but our participating faculty and financial support also come from several other UW schools and colleges: College of Agriculture and Life Sciences (CALS), School of Pharmacy (SOP), School of Veterinary Medicine (SVM), College of Letters & Science (L&S) and College of Engineering (COE). It is a truly interdisciplinary, cross-campus center.



  • Heyne GW1, Everson JL2, Ansen-Wilson LJ1, Melberg CG1, Fink DM1, Parins KF1, Doroodchi P1, Ulschmid CM1, Lipinski RJ3. Gli2 gene dosage and gene-environment interaction illuminate the etiological complexity of holoprosencephaly. Dis Model Mech. 2016 Sep 1. pii: dmm.026328. [Epub ahead of print]
  • Chesney A, Booth CJ, Lietz CB, Li L, Pedersen JA. Peroxymonosulfate Rapidly Inactivates the Disease-associated Prion Protein. Environ Sci Technol. 2016 Jun 1. [Epub ahead of print]. PMID: 27247993.
  • Fei P, Palenski TL, Wang S, Gurel Z, Hankenson KD, Sorenson CM, Sheibani N. Thrombospondin-2 Expression During Retinal Vascular Development and Neovascularization. J Ocul Pharmacol Ther. 2015 Sep;31(7):429-44. doi: 10.1089/jop.2014.0151. Epub 2015 May 7. PMID: 25950258.
  • Burns FR, Lanham KA, Xiong KM, Gooding AJ, Peterson RE, Heideman W. Analysis of the Zebrafish sox9b Promoter: Identifiecation of Elements that Recapitulate Organ-Specific Expression of sox9b. Gene. 2016 Mar 10; 578(2): 281-9. doi: 10.1016/j.gene.2015.12.041. Epub 2015 Dec 2013. PMID: 26721460.
  • Guo W, Yu D, Wang X, Luo C, Chen Y, Lei W, Wang C, Ge Y, Xue W, Tian Q, Gao X, Yao W. Anti-inflammatory effects of Interleukin-23 receptor cytokine-binding homology region rebalance T cell distribution in rodent collagen-induced arthritis. Oncotarget. 2016 May 11. doi: 10.18632/oncotarget.9309. [Epub ahead of print] PMID: 27177334


Make_a_gift_button_2Financial support is greatly appreciated, especially for graduate student support in areas with less Federal funding.